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Analysis of the PGC1β/Ppargc1b-regulated transcriptome in IL-4 and IFNγ-treated mouse macrophages
Overview
Dataset Name :
Analysis of the PGC1β/Ppargc1b-regulated transcriptome in IL-4 and IFNγ-treated mouse macrophages
Description :
Bone marrow-derived macrophages from wild type and PGC1β/Ppargc1b null mutant mice were treated with and without 10 ng/ml IL-4 or IFNγ for 12 h.
Dataset Type :
Transcriptomic
Release Date :
December 10, 2015
DOI :
10.1621/d3Q9ogpDw6
Version :
This is Version 1.0 of an annotated derivative of the original dataset, which can be found in NURSA
Dataset Citation :
Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V and Evans RM (2007) Analysis of the PGC1β/Ppargc1b-regulated transcriptome in IL-4 and IFNγ-treated mouse macrophages, v 1.0 Signaling Pathways Project Datasets. 10.1621/d3Q9ogpDw6
Download Citation :

Associated Article :
Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V and Evans RM (2007) Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense. Genes Dev. 21 1909-20 View Abstract | View PubMed | View Article
Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.

Experiments

There are 2 Experiments for this dataset. Up to the 50 up and down p < 0.05 FDR data points are displayed for each. Please download the dataset to view all data points.

  • 1 | PGC1β/Ppargc1b KO vs WT (IL4)
  • 2 | PGC1β/Ppargc1b KO vs WT (IFNγ)
Gene List
Experiment Information
Name : PGC1β/Ppargc1b KO vs WT (IL4)
Description :

Bone marrow-derived macrophages from PGC1β/Ppargc1b null mutant and wild-type male mice were treated with 10 ng/ml IL-4 for 12 h. This expression dataset was not included in the publication referenced but is relevant to the study.

Tissue/Cell line : myeloid lineage, macrophages, bone marrow-derived
Species : House Mouse
Additional Information