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Analysis of the MEK1/2-regulated transcriptome in R5020-treated human T47D cells
Overview
Dataset Name :
Analysis of the MEK1/2-regulated transcriptome in R5020-treated human T47D cells
Description :
Human T47D breast cancer cells were treated with or without a combination of (1) vehicle or (2) 10 µM U0126 (a MEK 1/2 kinase inhibitor) for 10 minutes, followed by 10 nM R5020 for 24 h.
Dataset Type :
Transcriptomic
Release Date :
March 28, 2015
DOI :
10.1621/XGSeVZH1LR
Version :
This is Version 1.0 of an annotated derivative of the original dataset, which can be found in GSE18276
Dataset Citation :
Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC and McDonnell DP (2010) Analysis of the MEK1/2-regulated transcriptome in R5020-treated human T47D cells, v 1.0 Signaling Pathways Project Datasets. 10.1621/XGSeVZH1LR
Download Citation :

Associated Article :
Wade HE, Kobayashi S, Eaton ML, Jansen MS, Lobenhofer EK, Lupien M, Geistlinger TR, Zhu W, Nevins JR, Brown M, Otteson DC and McDonnell DP (2010) Multimodal regulation of E2F1 gene expression by progestins. Mol. Cell. Biol. 30 1866-77 View Abstract | View PubMed | View Article
Multimodal regulation of E2F1 gene expression by progestins.

Experiments

There are 2 Experiments for this dataset. Up to the 50 up and down p < 0.05 FDR data points are displayed for each. Please download the dataset to view all data points.

  • 2 | R5020 + U0126 vs Veh
  • 3 | U0126 vs Veh (R5020)
Gene List
Experiment Information
Name : R5020 + U0126 vs Veh
Description :

Human T47D breast cancer cells were treated with or without a combination of 10 µM U0126 (a MEK 1/2 kinase inhibitor) for 10 minutes followed by 10 nM R5020 for 24 h.

Tissue/Cell line : epithelium, T47D cells
Species : Human
Additional Information